Good Combination and Bad Combination

Bad Combination for Heifers

ANGUSJournal ■ August 2008 I is hard enough breeding heifers under the best of conditions, so when heat stress and endophyte-infected fescue are added to the mix, reproductive systems, pregnancy rates and the long-term bottom line are all bound to suffer. Dave Patterson, University of Missouri Extension researcher and reproductive specialist, notes that reproductive performance is the most impo...

Digitalis and hemodialysis is a bad combination.

Too bad! Fixed dose combination antiretroviral drugs

Materials and methods 1681 HIV positive patients accessing care at Suntreso STI/HIV Clinic in Kumasi, who have been on treatment for more than 12 months and consented to participate were recruited for this cross sectional study. They were interviewed using semi-structured pre-texted questionnaire prior to the commencement of the new fixed dose combination ARVs treatment regime. Data was entered...

Bim, Bad, and Bax: a deadly combination in epileptic seizures.

Several Bcl-2 family members, including Bim, may contribute to programmed cell death by inducing mitochondrial cytochrome c release, which activates caspase-9 and then caspase-3, the "executioner" of the cell. In this issue of the JCI, Shinoda and collaborators show the key role of Bim in epileptic seizure-induced neuronal injury and identify the contribution of transcription factors responsibl...

Rumination and cigarette smoking: a bad combination for depressive outcomes?

Ruminative coping has been shown to heighten the risk and severity of depression. The authors hypothesized that ruminators who smoke would experience greater depressive symptoms than ruminators who do not. The rationale is that, by heightening attentional focus, nicotine may increase ruminators' ability to focus on negative thoughts, augmenting depressed mood. Participants (N = 145) self-report...